Cullin7 induces docetaxel resistance by regulating the protein level of the antiapoptotic protein Survivin in lung adenocarcinoma cells
نویسندگان
چکیده
Background: Lung adenocarcinoma (LUAD) is the most common subtype of non-small cell lung cancer (NSCLC). Chemotherapy resistance main cause chemotherapy failure. Cullin7 (Cul7) highly expressed in LUAD and associated with poor prognosis. Moreover, Cul7 abnormally overexpressed docetaxel-resistant cells. Therefore, further exploration role molecular mechanism docetaxel necessary.
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ژورنال
عنوان ژورنال: Journal of Thoracic Disease
سال: 2023
ISSN: ['2077-6624', '2072-1439']
DOI: https://doi.org/10.21037/jtd-23-1110